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The gross and fine motor delays were frequently associated with a moderate to severe language dysfunction which adversely affected classroom performance. How to cite this comment: Neuromuscular deficits have been described in 47,XXY and 47,XYY boys, but gross and fine motor development of girls with sex chromosome aneuploidy has not been extensively studied. Gov't Research Support, U. Regular developmental assessments of children with sex chromosome aneuploidy, including sensory-motor integration, should assist in the identification of early developmental delays and permit appropriate intervention. Add to My Bibliography. The clinical assessment confirmed the BOTMP findings, with 13 propositae exhibiting dysfunctional sensory-motor integration.

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